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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNNI3K All Species: 13.33
Human Site: S883 Identified Species: 29.33
UniProt: Q59H18 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q59H18 NP_001106279.1 936 104179 S883 A R S Y A A L S Q S A G Q Y S
Chimpanzee Pan troglodytes XP_513493 949 105567 S896 A R S Y A A L S Q S A G Q Y S
Rhesus Macaque Macaca mulatta XP_001097254 949 105560 S896 A R S Y A A L S Q S A G Q H S
Dog Lupus familis XP_537112 1087 119299 S1034 S H V A A L R S R F E L E Y A
Cat Felis silvestris
Mouse Mus musculus Q5GIG6 834 92569 Q782 R S Y T G W P Q S V G T H T N
Rat Rattus norvegicus Q7TQP6 835 92713 Q783 R S Y A G W S Q S V G T H S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339957 835 92821 Q783 R A Y A F W T Q N S A R R S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001021182 850 93167 S798 I S A P S T V S Q L T S Q W E
Sea Urchin Strong. purpuratus XP_782227 862 95496 V810 G E L P A G N V T A L R T Q W
Poplar Tree Populus trichocarpa XP_002336079 539 60951 H487 L R P S I P S H S H P K L A E
Maize Zea mays NP_001152032 543 61643 H491 L D I P G S V H P R L T K L I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 96.5 80.1 N.A. 80.7 81.3 N.A. N.A. N.A. N.A. 75.7 N.A. N.A. N.A. 36.7 51.1
Protein Similarity: 100 98.3 97.2 82.6 N.A. 84.4 85.3 N.A. N.A. N.A. N.A. 83.7 N.A. N.A. N.A. 55 65.6
P-Site Identity: 100 100 93.3 20 N.A. 0 0 N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 100 100 46.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 26.6 N.A. N.A. N.A. 46.6 13.3
Percent
Protein Identity: 23.6 22.4 N.A. N.A. N.A. N.A.
Protein Similarity: 37.2 36.2 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 10 10 28 46 28 0 0 0 10 37 0 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 19 % E
% Phe: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 10 0 0 0 28 10 0 0 0 0 19 28 0 0 0 % G
% His: 0 10 0 0 0 0 0 19 0 10 0 0 19 10 0 % H
% Ile: 10 0 10 0 10 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % K
% Leu: 19 0 10 0 0 10 28 0 0 10 19 10 10 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 19 % N
% Pro: 0 0 10 28 0 10 10 0 10 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 28 37 0 0 0 37 10 0 % Q
% Arg: 28 37 0 0 0 0 10 0 10 10 0 19 10 0 0 % R
% Ser: 10 28 28 10 10 10 19 46 28 37 0 10 0 19 37 % S
% Thr: 0 0 0 10 0 10 10 0 10 0 10 28 10 10 0 % T
% Val: 0 0 10 0 0 0 19 10 0 19 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 28 0 0 0 0 0 0 0 10 10 % W
% Tyr: 0 0 28 28 0 0 0 0 0 0 0 0 0 28 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _